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PAD-2- mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

by admin | Feb 14, 2022 | Moditope, Vaccines

Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant ABSTRACT:Background The enzymatic conversion of arginine to citrulline is involved in gene and protein...

An Immunohistochemical Evaluation of Tumor-Associated Glycans and Mucins as Targets for Molecular Imaging of Pancreatic Ductal Adenocarcinoma

by admin | Feb 14, 2022 | Antibodies, Glymab

Ruben D. Houvast, Kira Thijse, Jesse V. Groen, JiaXin Chua, Mireille Vankemmelbeke, Lindy G. Durrant, J. Sven D. Mieog, Bert A. Bonsing, Alexander L. Vahrmeijer, Peter J.K. Kuppen, A. Stijn L.P. Crobach and Cornelis F. M. Sier SIMPLE SUMMARY: Distinguishing pancreatic...

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging

by admin | Feb 14, 2022 | Antibodies, Glymab

Ruben D. Houvast, Mireille Vankemmelbeke, Lindy G. Durrant, Manfred Wuhrer, Victor M. Baart, Peter J.K. Kuppen, Lioe-Fee de Geus-Oei, Alexander L. Vahrmeijer and Cornelis F.M. Sier SIMPLE SUMMARY: Distinguishing malignancy from healthy tissue is essential for...