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Vaccine Can Induce CD4-Mediated Responses to Homocitrullinated Peptides via Multiple HLA-Types and Confer Anti-Tumor Immunity

by admin | Apr 12, 2022 | Moditope, Vaccines

Katherine Cook, Wei Xue, Suha Atabani, Peter Symonds, Abdullah Al Omari, Ian Daniels, Sabaria Shah, Ruhul Hasan Choudhury, Daisy Weston, Rachael Metheringham, Victoria Brentville and Lindy Durrant ABSTRACT: Homocitrullination is the post translation modification (PTM)...

PAD-2- mediated citrullination of nucleophosmin provides an effective target for tumor immunotherapy

by admin | Feb 14, 2022 | Moditope, Vaccines

Ruhul H Choudhury, Peter Symonds, Samantha J Paston, Ian Daniels, Katherine W Cook, Mohamed Gijon, Rachael L Metheringham, Victoria A Brentville, Lindy G Durrant ABSTRACT:Background The enzymatic conversion of arginine to citrulline is involved in gene and protein...
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Scancell is focused on developing novel immunotherapies for the treatment of cancer and was founded in 1996 based on research led by Professor Lindy Durrant at the University of Nottingham in the UK.

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